trinexapac ethyl trade names

Avoid contact with skin and eyes. There are no residual uncertainties in the exposure database. Due to the low acute toxicity of trinexapac-ethyl the allocation of an ARfD, and hence an acute consumer risk assessment was not considered necessary. 4-(cyclopropyl-hydroxy methylene)-3,5-dioxo- cyclohexanecarboxylic acid ethyl ester 4-(cyclopropyl-hydroxy-methylene)-3,5-dioxo-cyclohexanecarboxylic acid ethyl esterTrinexapac-ethylethyl (RS)-4-cyclopropyl(hydroxy)methylene-3,5-dioxocyclohexanecarboxylateethyl 4-cyclopropyl(hydroxy)methylene-3,5-dioxocyclohexanecarboxylate, Moddus;ethyl 4-[cyclopropyl(hydroxy)methylidene]-3,5-dioxocyclohexane-1-carboxylate;Trinexapac-ethyl. Provision to contain effluent from fire extinguishing. Trade Capacity. This site displays a prototype of a Web 2.0 version of the daily [FR Doc. ), EPA will submit a report containing this rule and other required information to the U.S. Senate, the U.S. House of Representatives, and the Comptroller General of the United States prior to publication of the rule in the Federal Register. The Docket Facility telephone number is (703) 305-5805. Home; Product . Additionally, T-NEX is the perfect pre-stress conditioning choice for the coming season. Application of Palisade or Palisade plus Tilt increased grain yield at Chickasha and had no effect on grain yield at Stillwater or Perkins in 2013. An endpoint of concern was not identified for the general U.S. population; however, the acute dietary assessment is protective of women that may become pregnant. Tech Grade: 96% TC: Formulation: 25% EC . Neither comment was accompanied by any substantiation nor data supporting a conclusion that the tolerances being established in this action do not meet the FFDCA safety standard. NO open flames. Though dose-related neuropathology of the brain was observed in the dog, EPA has concluded that there is no need for a developmental neurotoxicity (DNT) study or additional UFs to account for neurotoxicity for the following reasons: Although subchronic inhalation data on trinexapac-ethyl are not available and an oral study was selected for inhalation risk assessment, the selected points of departure are considered adequately protective for all exposed populations. In our study we evaluated 12 oz/ac of Palisade with and without 4 oz/ac of Tilt (propiconazole) applied at Feekes GS 7 (two nodes visible above the soil surface). Application of Palisade or Palisade plus Tilt increased grain yield at Perkins in 2014 even though there was no lodging. Ensure adequate ventilation. In applying this provision, EPA either retains the default value of 10X, or uses a different additional safety factor when reliable data available to EPA support the choice of a different factor. Based upon review of the data supporting the petition, EPA has revised most of the proposed tolerance levels, added tolerances for hog fat and meat, and deleted the proposed tolerance for cattle kidney. Trinexapac-ethyl 4-()-3,5-4-(Cyclopropyl-alpha-hydroxymethylene)-3,5-dioxo-cyclohexanecarboxylic acid ethyl ester C13H16O5 252.27 FW252.27 36.0mp36.0>270bp>270pKa: 4.71.6mPa(20) 2.16mpa(25)(20g/L)2.8(pH 4.9)10.2(pH 5.5)21.1(pH 8.2)5% Section 408(b)(2)(C) of FFDCA provides that EPA shall apply an additional tenfold (10X) margin of safety for infants and children in the case of threshold effects to account for prenatal and postnatal toxicity and the completeness of the database on toxicity and exposure unless EPA determines based on reliable data that a different margin of safety will be safe for infants and children. Based on these risk assessments, EPA concludes that there is a reasonable certainty that no harm will result to the general population, or to infants and children from aggregate exposure to trinexapac-ethyl residues. on This regulation is effective March 2, 2012. 272 note). Federal Register. That decision is based on the following findings: i. hVk0W=}Xd(&[Xa+ KLbH{lww%K/c?t/I_"E&`Rd)ZS1DI3kxJ _vOU\,P 3ee2'mF3[A6Q`'^?cOvnLT`#L~[nrM-u=l >W==VnoM}?6vQ7K~W7MWIfK{ _uxP!uL [?]K@_PY`,dOcrT+y0e[zj~"PNsZCP}^SPL##P>3@Z. Short- and intermediate-term risk. Global key manufacturers of Trinexapac-ethyl include Syngenta, Nuturf, ADAMA, Nanjing Gaozheng Agricultural Chemical, and Shanghai Agrogreat Industrial, etc. These markup elements allow the user to see how the document follows the The petition requested that 40 CFR part 180.662 be amended by establishing tolerances for residues of the herbicide trinexapac-ethyl, (4-(cyclopropyl-a-hydroxy-methylene)-3,5-dioxo-cyclohexanecarboxylic acid ethyl ester), and its primary metabolite CGA-179500 in or on sugarcane, cane at 1.5 parts per million (ppm) and sugarcane, molasses at 5.0 ppm. Trinexapac-ethyl is classified as "Not likely to be carcinogenic to humans." The combined chronic toxicity/carcinogenicity study in the rat did not demonstrate an increase in any tumor type that would be relevant to humans. Important Announcement. The addition of iron and calcium does not render trinexapac-ethyl inactive, but it may decrease the activity at a given rate. (We`ll never share your email address with a third-party.). Palisade is a giberellic acid inhibitor and works primarily by reducing plant height. Avoid formation of dust and aerosols. 02/28/2023, 205 There are clear NOAELs/LOAELs for this effect; in which the NOAEL dose is 10-fold lower than the LOAEL dose at which neuropathology is observed, and is therefore sufficiently protective. This repetition of headings to form internal navigation links 02/28/2023, 267 the official SGML-based PDF version on govinfo.gov, those relying on it for Consider lowering your first application rates. Therefore, EPA is increasing tolerances for residues of trinexapac-ethyl, ethyl 4-(cyclopropylhydroxymethylene)-3,5-dioxocyclohexanecarboxylate, including Start Printed Page 70064its metabolites and degradates, in or on sugarcane, cane at 1.5 ppm, and sugarcane, molasses at 5 ppm. The lesions remained confined to the supporting cells in the central nervous system and did not progress to more advanced or more extensive damage of the nervous tissue. Research has shown that increasing the soil water content from 17 to 26% reduced the force required for anchorage failure by 33%, and as little as 0.25 inches of water plus 11 mph winds were enough to cause lodging. Quantitative acute dietary exposure and risk assessments are performed for a food-use pesticide, if a toxicological study has indicated the possibility of an effect of concern Start Printed Page 12743occurring as a result of a 1-day or single exposure. Prevent fire caused by electrostatic discharge steam. Section 408(b)(2)(C) of FFDCA requires EPA to give special consideration to exposure of infants and children to the pesticide chemical residue in establishing a tolerance and to ensure that there is a reasonable certainty that no harm will result to infants and children from aggregate exposure to the pesticide chemical residue. Molecular Formula CHO. III. Submit the non-CBI copy of your objection or hearing request, identified by docket ID number EPA-HQ-OPP-2020-0046, by one of the following methods: Additional instructions on commenting or visiting the docket, along with more information about dockets generally, is available at http://www.epa.gov/dockets. 2. Because these products primarily affect cell elongation and not division, the number of new cells is only slightly reduced while their ability to elongate is significantly altered. 02/28/2023, 43 1. Each document posted on the site includes a link to the on Cancer. documents in the last year, 522 the current document as it appeared on Public Inspection on This prototype edition of the error_outlineEmergency Number01484 538 444. Quick Resources. Employees. . Therefore, an additional 10x database UF was not retained for lack of inhalation toxicity data and these data are not being required. Syngenta Crop Protection, Inc. requested these tolerances under the Federal Food, Drug, and Cosmetic Act (FFDCA). EPA published a final rule in the Federal Register on May 20, 2015 (80 FR 28843) (FRL-9926-62) establishing tolerances for residues of trinexapac-ethyl in or on rice and rye commodities based on the Agency's conclusion that there is a reasonable certainty that no harm will result from aggregate exposure to trinexapac-ethyl to the general population, including infants and children. Inquiry Basket () February,13th,2023; Hebei Luantong trade.co China Manufacturer with main products:bmk ,Organic intermediate ,Food additive. Any trinexapac-ethyl that hits the soil is lost. 1503 & 1507. The Docket Facility is open from 8:30 a.m. to 4 p.m., Monday through Friday, excluding legal holidays. Pesticide Review Status. Based on the residential use patterns for trinexapac-ethyl, chronic residential exposure to residues is not expected. documents in the last year, 83 4. EPA may establish a tolerance that is different from a Codex MRL; however, FFDCA section 408(b)(4) requires that EPA explain the reasons for departing from the Codex level. headings within the legal text of Federal Register documents. Trinexapac Ethyl improves rich color and root mass development. Full disclosure: Syngenta donated the product for this trial, but the only funding for the research was provided by the Oklahoma Agricultural Experiment Station and the Oklahoma Cooperative Extension Service. Because the acute and chronic dietary exposure estimates were based on several conservative assumptions (100% of crops treated with residues present at tolerance levels, default processing factors and screening level drinking water estimates), EPA is confident that the dietary exposure assessments do not underestimate risk to the general U.S. population and various population subgroups. Pesticide Review Status. You may be potentially affected by this action if you are an agricultural producer, food manufacturer, or pesticide manufacturer. documents in the last year, 121 Document Drafting Handbook Open for Comment, Economic Sanctions & Foreign Assets Control, Electric Vehicle Standards and Requirements, Further Advancing Racial Equity and Support for Underserved Communities Through the Federal Government, Addendum to the Human Health Risk Assessment for Trinexapac-ethyl, Revised Residue Chemistry Chapter for Triexapac-ethyl. All Rights Reserved. 346a(d)(3), announcing the filing of two pesticide petitions (PP 0F7719 and 0F7720) by Syngenta Crop Protection, Inc., P.O. EPA considers the international maximum residue limits (MRLs) established by the Codex Alimentarius Commission (Codex), as required by FFDCA section 408(b)(4).

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